Andrew Murphy was born in Sydney, Australia. He began his dance training in Canberra with Betsy Sawers and Sandra Griffin. Andrew joined The Australian Ballet in 1989 where he rose to the rank of senior artist. Andrew also danced as a principal artist with the Birmingham Royal Ballet and the Houston Ballet. He has performed leading roles in all the major classical productions, as well as in a wide range of contemporary ballets including works by Frederick Ashton, George Balanchine, James Kudelka, Natalie Weir, John Cranko, Twyla Tharp, Jerome Robbins, and Kenneth McMillan. Andrew also personally worked with great choreographers such as David Bintley, Jiří Kylián, Christopher Bruce, Glen Tetley, Ben Stevenson, Stephen Baynes, Ronald Hynd, Stanton Welch, Mark Morris, Hans Van Manen, and Graeme Murphy AO.

After retiring from the stage in 2008, Andrew joined the staff of Houston Ballet Academy where he became Principal Instructor and Boys Program Coordinator. He participated in the collaboration between Houston Ballet Second Company and San Francisco Trainee Performances and has coached many Prix de Lausanne participants and Prize Winners.

Andrew has taught as a guest for Houston Ballet, The Australian Ballet, Studio Wayne Macgregor, Colorado Ballet, Colorado Ballet School and the University of Hawaii. Andrew Murphy joined The Australian Ballet School as Artistic Teacher of Classical Dance and Ballet
Master in 2017.